“Equine osteoarthritis is an important cause of lameness and elimination in sports horses, and traditional treatment is difficult to improve the joint microenvironment. Researchers included 8 healthy horses for 14 day safety observation and 10 naturally occurring OA horses for 28 day treatment efficacy evaluation and follow-up, as well as synovial proteomic analysis, to verify the safety and clinical effectiveness of adipose derived mesenchymal stem cell therapy for equine osteoarthritis. This provides a solution to the clinical translation problem of equine osteoarthritis.”