“In order to understand the epidemiological characteristics of the main pathogens causing calf diarrhea in large-scale breeding farms in northern China, the research progress in animal disease prevention and control was introduced. The research team established a multi pathogen detection and analysis system and explored the epidemic patterns of calf diarrhea pathogens from 2019 to 2024, providing a reference for accurate monitoring and comprehensive prevention and control of calf diarrhea.”