CircANKEF1 regulates the proliferation, apoptosis and differentiation of bovine preadipocytes through the miR-183/EGR1, miR-127/MAPK4 and miR-129/CDK6 axes

BAI Xue; WANG Shuzhe; YANG Mengli; JI Guoshang; LIU Yuan; CHU Hongen; LI Fen; CAI Bei; MA Yun

doi:10.11841/j.issn.1007-4333.2026.05.13

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CircANKEF1 regulates the proliferation, apoptosis and differentiation of bovine preadipocytes through the miR-183/EGR1, miR-127/MAPK4 and miR-129/CDK6 axes

Updated：2026-04-10

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- CircANKEF1 regulates the proliferation, apoptosis and differentiation of bovine preadipocytes through the miR-183/EGR1, miR-127/MAPK4 and miR-129/CDK6 axes
- “The research progress of circANKEF1 in the field of proliferation and differentiation of bovine preadipocytes was introduced. Experts explored the specific mechanism of circANKEF1 as a molecular sponge targeting miRNA and mRNA regulation, providing a theoretical basis for a deeper understanding of the molecular regulatory mechanism of intramuscular fat development in beef cattle.”
- BAI Xue , WANG Shuzhe , YANG Mengli , JI Guoshang , LIU Yuan , CHU Hongen , LI Fen , CAI Bei , MA Yun
- Journal of China Agricultural University Vol. 31, Issue 5, Pages: 154-165(2026)
- Affiliations：
  1.College of Animal Science and Technology/Key Laboratory of Precisim Breeding and Nutritional Regulation for Dominam and characteristic Livestock and Poultry in Ningxia， Ningxia University， Yinchuan 750021， China
  2.College of Animal Science and Technology， Xichang University， Xichang 615013， China
  3.Faculty of Life and Food Sciences， Ningxia University， Yinchuan 750021， China
- Author bio：
- Funds：
- DOI： 10.11841/j.issn.1007-4333.2026.05.13
  CLC：
- Accepted：14 January 2026 ，
- Accepted：
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CircANKEF1 regulates the proliferation, apoptosis and differentiation of bovine preadipocytes through the miR-183/EGR1, miR-127/MAPK4 and miR-129/CDK6 axes

DOI： 10.11841/j.issn.1007-4333.2026.05.13

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